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Cannabinoid Deep Dive, Issue No. 2: CBG – “The Mother of All Cannabinoids”

Cannabinoid Deep Dive, Issue No. 2: CBG – “The Mother of All Cannabinoids”

Jun 2, 20253 min read

Welcome back to Cannabinoid Deep Dive — our series where we explore the many faces of cannabis beyond just THC and CBD. In each issue, we unpack a different cannabinoid, explain how it works with your body, and explore why it matters for your health and wellness.

Today, we’re talking about CBG (cannabigerol) — often called the Mother of All Cannabinoids. Why? Because without it, you wouldn’t have THC, CBD, or a lot of the other cannabinoids we’re just beginning to understand.


What Is CBG?

CBG might not be as well-known as THC or CBD, but it plays a starring role behind the scenes. It starts as CBGA (cannabigerolic acid), which is the very first cannabinoid acid formed in the cannabis plant. From there, enzymes help convert it into other major cannabinoids like THCA, CBDA, and CBCA. When these acidic compounds are heated, they become the active forms we know as THC, CBD, and CBG.

So while CBG is usually found in small amounts in most strains, it’s absolutely essential. Some modern growers are even breeding cannabis strains specifically to retain more CBG by slowing down that natural conversion process.


Why We’re Just Learning About It Now

You might be wondering: if CBG was discovered back in 1964 (by none other than Dr. Raphael Mechoulam), why are we only hearing about it now? Simple: cannabis was labeled a Schedule 1 drug in 1970, right alongside heroin and LSD. That classification made it nearly impossible to study.

Before that, the Marihuana Tax Act of 1937 had already thrown a wrench in the works, and even the cannabis used in federally approved research wasn’t representative of what people were actually consuming. It wasn’t until states began creating their own medical and recreational programs that researchers could really dig in and start studying cannabis properly.


What CBG Might Help With

CBG is non-psychoactive, meaning it won’t get you high. But what it might do is pretty impressive. Early research shows CBG has anti-inflammatory properties that could help with arthritis, IBD, and chronic pain. It may also have neuroprotective effects, potentially benefiting conditions like Parkinson’s, Alzheimer’s, and Huntington’s.

It’s also being studied for its ability to reduce intraocular pressure (great news for glaucoma sufferers), stimulate appetite, and offer anxiety and depression relief without the side effects of pharmaceuticals.

CBG has shown antibacterial power, too — especially against tough-to-kill bugs like MRSA. It might even help with skin issues like eczema, acne, and psoriasis, thanks to its ability to calm inflammation and fight bacteria.

And while it’s still early, there’s growing curiosity around CBG’s potential role in cancer treatment, especially in relation to how it might affect cell growth.


Looking Ahead

CBG may be present in tiny amounts in most cannabis strains, but its potential is anything but small. As modern science catches up to ancient wisdom, cannabinoids like CBG are starting to take the spotlight.

With more research, better access, and smarter cultivation, we’re finally starting to unlock what this plant can really do. And CBG? It just might be leading the charge.

In the next issue, we’ll take a closer look at CBN — “The Sleepy One.” Stay tuned!

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Article written by:

David Yrigoyen

David Yrigoyen

More about David
Tucson Foodie is Tucson's premier food and dining publication, covering the best restaurants, events, and culinary experiences in Southern Arizona.

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José Contreras, chef and owner of @Ameliastucson, is headed to New York City to cook alongside chef Alam Méndez of Washington, D.C.‘s Apapacho Taqueria for a collaborative dinner at the James Beard Foundation’s Platform at Pier 57.

The Aug. 11 dinner will celebrate the culinary traditions of Sonora and Oaxaca through a multi course menu centered on heirloom corn, traditional masa, and coastal flavors. Guests will also enjoy a cocktail reception, Mijenta Tequila pairings, and a Q&A with both chefs. The event begins at 6:30 pm at @Pier57.nyc. Tickets are $210 for dining table seats and $250 for the chef’s counter, and are available now at Jamesbeard.org.

Congratulations to @Chefjosetucson on another incredible milestone!🎉

Read @Jackie_tran_’s article on Tucsonfoodie.com

#tucsonaz #tucsonnewsJosé Contreras, chef and owner of @Ameliastucson, is headed to New York City to cook alongside chef Alam Méndez of Washington, D.C.‘s Apapacho Taqueria for a collaborative dinner at the James Beard Foundation’s Platform at Pier 57. The Aug. 11 dinner will celebrate the culinary traditions of Sonora and Oaxaca through a multi course menu centered on heirloom corn, traditional masa, and coastal flavors. Guests will also enjoy a cocktail reception, Mijenta Tequila pairings, and a Q&A with both chefs. The event begins at 6:30 pm at @Pier57.nyc. Tickets are $210 for dining table seats and $250 for the chef’s counter, and are available now at Jamesbeard.org. Congratulations to @Chefjosetucson on another incredible milestone!🎉 Read @Jackie_tran_’s article on Tucsonfoodie.com #tucsonaz #tucsonnewsItalian Week starts today, and we’re sharing this sweet video of @Spaghettioftucson doing what she did best: bringing smiles to everyone around her.

Our hearts are with her family today. We’ll love you and miss you forever, Spaghetti.❤️‍🩹🐶Italian Week starts today, and we’re sharing this sweet video of @Spaghettioftucson doing what she did best: bringing smiles to everyone around her. Our hearts are with her family today. We’ll love you and miss you forever, Spaghetti.❤️‍🩹🐶Italian Week starts today and runs through July 19 as part of 12 Weeks of Foodie Summer!🍝

Support Tucson’s classic and modern Italian restaurants, then upload your receipt at summer.tucsonfoodie.com for a chance to win weekly prizes and the grand prize at the end of August.

🎉 Week 5 Winners
• Libby: $50 North Italia gift card
• Keely: America’s Best Mexican Food Festival tickets
• arts_primacy_2c: 4 Cool Summer Nights passes
• Donita3000: $20 Ghini’s French Caffe gift card
• Nancy & Gabriella: $100 Visa gift cards

Italian Week Deal: @reneestucson is offering buy one, get one 50% off (equal or lesser value) for dine-in or takeout. Just mention you’re a Tucson Foodie fan. Exclusions apply.

🏆 This Week’s Prizes
• $50 @fentonellispizzeria gift card
• $100 Visa gift card
• $75 @carusositalian gift card
• $20 @ghinisfrenchcaffe gift card
• $50 @miramontetucson gift card
• $50 @localetucson gift card
• @desertmuseum passes 

More details in bio!Italian Week starts today and runs through July 19 as part of 12 Weeks of Foodie Summer!🍝 Support Tucson’s classic and modern Italian restaurants, then upload your receipt at summer.tucsonfoodie.com for a chance to win weekly prizes and the grand prize at the end of August. 🎉 Week 5 Winners • Libby: $50 North Italia gift card • Keely: America’s Best Mexican Food Festival tickets • arts_primacy_2c: 4 Cool Summer Nights passes • Donita3000: $20 Ghini’s French Caffe gift card • Nancy & Gabriella: $100 Visa gift cards Italian Week Deal: @reneestucson is offering buy one, get one 50% off (equal or lesser value) for dine-in or takeout. Just mention you’re a Tucson Foodie fan. Exclusions apply. 🏆 This Week’s Prizes • $50 @fentonellispizzeria gift card • $100 Visa gift card • $75 @carusositalian gift card • $20 @ghinisfrenchcaffe gift card • $50 @miramontetucson gift card • $50 @localetucson gift card • @desertmuseum passes More details in bio!The Mercado District is one of Tucson’s best places to eat, drink, shop, and stroll, all in one stop.🐶❤️

Home to Mercado San Agustín, the MSA Annex, The Monier, and the upcoming Bautista development, there’s always something new to explore. Grab a bite, browse local shops, enjoy the open-air courtyards (they’re dog-friendly!), or hop on the free Sun Link streetcar, which stops right at the Mercado. 

MERCADO SAN AGUSTÍN:
@agustinkitchen 
@seiskitchen 
@prestacoffee 
@laestrella_tucson 
@dolcepastellocakes 
@zumitosjuicebar 
@santacruzriverfm 

MSA ANNEX:
@decibelcoffeeworks 
@kukai___ 
@bosburger__ 
@hidden_hearth 
@rolliestucson 
@westbound_tapandbottle 

THE MONIER:
@wholeslvcepizza 
@81barbersofficial 

Share your favorite stops with us!
More details on Tucsonfoodie.com 

#tucson #tucsonfoodieThe Mercado District is one of Tucson’s best places to eat, drink, shop, and stroll, all in one stop.🐶❤️ Home to Mercado San Agustín, the MSA Annex, The Monier, and the upcoming Bautista development, there’s always something new to explore. Grab a bite, browse local shops, enjoy the open-air courtyards (they’re dog-friendly!), or hop on the free Sun Link streetcar, which stops right at the Mercado. MERCADO SAN AGUSTÍN: @agustinkitchen @seiskitchen @prestacoffee @laestrella_tucson @dolcepastellocakes @zumitosjuicebar @santacruzriverfm MSA ANNEX: @decibelcoffeeworks @kukai___ @bosburger__ @hidden_hearth @rolliestucson @westbound_tapandbottle THE MONIER: @wholeslvcepizza @81barbersofficial Share your favorite stops with us! More details on Tucsonfoodie.com #tucson #tucsonfoodieTwo days at @Hiltonelcon felt like the ultimate staycation. Between the pools, hot spring and cold plunge, water slide, yoga, live music, complimentary bike rentals, and their nostalgic “Summer Rewind” experience, there was always something to do. We never left the resort. 

The highlight at their on-site restaurant, Epazote Kitchen & Cocktails, was the Pollo Con Rajas - perfectly cooked chicken over a rich creamed poblano, onion, and corn mestizaje. And if you’re at their Sundance Café for breakfast, get the pozole. It’s made from a family recipe that became such a guest favorite it earned a permanent spot on the menu. 

Although El Conquistador licenses the Hilton brand, it’s owned and operated by a local company. The culinary team sources much of its meat and produce from Arizona. 

Whether you’re planning a weekend getaway or just looking for an incredible dinner with Catalina Mountain views, this spot is worth adding to your list. 🌵🌞 

#tucsonaz #tucsonfoodieTwo days at @Hiltonelcon felt like the ultimate staycation. Between the pools, hot spring and cold plunge, water slide, yoga, live music, complimentary bike rentals, and their nostalgic “Summer Rewind” experience, there was always something to do. We never left the resort. The highlight at their on-site restaurant, Epazote Kitchen & Cocktails, was the Pollo Con Rajas - perfectly cooked chicken over a rich creamed poblano, onion, and corn mestizaje. And if you’re at their Sundance Café for breakfast, get the pozole. It’s made from a family recipe that became such a guest favorite it earned a permanent spot on the menu. Although El Conquistador licenses the Hilton brand, it’s owned and operated by a local company. The culinary team sources much of its meat and produce from Arizona. Whether you’re planning a weekend getaway or just looking for an incredible dinner with Catalina Mountain views, this spot is worth adding to your list. 🌵🌞 #tucsonaz #tucsonfoodieHow many receipts have you sent in for NEW-TO-ME week?💛

From July 6 through July 12, upload your receipt from ANY local business at summer.tucsonfoodie.com for a chance to win weekly prizes and earn entries toward the 12 Weeks of Foodie Summer grand prize drawing at the end of August. 🔗 in bio. 

ANY LOCAL SPOT COUNTS. 

WEEK 6 WINNERS
Here are the winners from Happy Hour Week:
* Libby wins a $50 gift card to North Italia
* Keely wins a ticket to America’s Best Mexican Food Festival
* arts_primacy_2c wins a four-pack of passes to Cool Summer Nights at the Arizona-Sonora Desert Museum
* donita3000 wins a $20 gift card to Ghini’s French Caffe
* Nancy wins a $100 Visa gift card
* Gabriella wins a $100 Visa gift card 

PRIZES
This week’s prize pool includes:
* Salsa, Taco, and Tequila Challenge tickets
* $100 Visa gift card
* @eljefecatcafe pass
* $20 @ghinisfrenchcaffe 
* @desertmuseum passes

Presenting sponsor: @visittucson
Presented by: @bbb_so_az • @510southtucson • @azwinecollectiveHow many receipts have you sent in for NEW-TO-ME week?💛 From July 6 through July 12, upload your receipt from ANY local business at summer.tucsonfoodie.com for a chance to win weekly prizes and earn entries toward the 12 Weeks of Foodie Summer grand prize drawing at the end of August. 🔗 in bio. ANY LOCAL SPOT COUNTS. WEEK 6 WINNERS Here are the winners from Happy Hour Week: * Libby wins a $50 gift card to North Italia * Keely wins a ticket to America’s Best Mexican Food Festival * arts_primacy_2c wins a four-pack of passes to Cool Summer Nights at the Arizona-Sonora Desert Museum * donita3000 wins a $20 gift card to Ghini’s French Caffe * Nancy wins a $100 Visa gift card * Gabriella wins a $100 Visa gift card PRIZES This week’s prize pool includes: * Salsa, Taco, and Tequila Challenge tickets * $100 Visa gift card * @eljefecatcafe pass * $20 @ghinisfrenchcaffe * @desertmuseum passes Presenting sponsor: @visittucson Presented by: @bbb_so_az • @510southtucson • @azwinecollective

Tag us @TUCSONFOODIE in your food adventures!