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Cannabinoid Deep Dive, Issue No. 2: CBG – “The Mother of All Cannabinoids”

The Endocannabinoid System

Cannabinoid Deep Dive, Issue No. 2: CBG – “The Mother of All Cannabinoids”

Jun 2, 20253 min read

Welcome back to Cannabinoid Deep Dive — our series where we explore the many faces of cannabis beyond just THC and CBD. In each issue, we unpack a different cannabinoid, explain how it works with your body, and explore why it matters for your health and wellness.

Today, we’re talking about CBG (cannabigerol) — often called the Mother of All Cannabinoids. Why? Because without it, you wouldn’t have THC, CBD, or a lot of the other cannabinoids we’re just beginning to understand.


What Is CBG?

CBG might not be as well-known as THC or CBD, but it plays a starring role behind the scenes. It starts as CBGA (cannabigerolic acid), which is the very first cannabinoid acid formed in the cannabis plant. From there, enzymes help convert it into other major cannabinoids like THCA, CBDA, and CBCA. When these acidic compounds are heated, they become the active forms we know as THC, CBD, and CBG.

So while CBG is usually found in small amounts in most strains, it’s absolutely essential. Some modern growers are even breeding cannabis strains specifically to retain more CBG by slowing down that natural conversion process.


Why We’re Just Learning About It Now

You might be wondering: if CBG was discovered back in 1964 (by none other than Dr. Raphael Mechoulam), why are we only hearing about it now? Simple: cannabis was labeled a Schedule 1 drug in 1970, right alongside heroin and LSD. That classification made it nearly impossible to study.

Before that, the Marihuana Tax Act of 1937 had already thrown a wrench in the works, and even the cannabis used in federally approved research wasn’t representative of what people were actually consuming. It wasn’t until states began creating their own medical and recreational programs that researchers could really dig in and start studying cannabis properly.


What CBG Might Help With

CBG is non-psychoactive, meaning it won’t get you high. But what it might do is pretty impressive. Early research shows CBG has anti-inflammatory properties that could help with arthritis, IBD, and chronic pain. It may also have neuroprotective effects, potentially benefiting conditions like Parkinson’s, Alzheimer’s, and Huntington’s.

It’s also being studied for its ability to reduce intraocular pressure (great news for glaucoma sufferers), stimulate appetite, and offer anxiety and depression relief without the side effects of pharmaceuticals.

CBG has shown antibacterial power, too — especially against tough-to-kill bugs like MRSA. It might even help with skin issues like eczema, acne, and psoriasis, thanks to its ability to calm inflammation and fight bacteria.

And while it’s still early, there’s growing curiosity around CBG’s potential role in cancer treatment, especially in relation to how it might affect cell growth.


Looking Ahead

CBG may be present in tiny amounts in most cannabis strains, but its potential is anything but small. As modern science catches up to ancient wisdom, cannabinoids like CBG are starting to take the spotlight.

With more research, better access, and smarter cultivation, we’re finally starting to unlock what this plant can really do. And CBG? It just might be leading the charge.

In the next issue, we’ll take a closer look at CBN — “The Sleepy One.” Stay tuned!

Article written by:

David Yrigoyen

David Yrigoyen

More about David
Tucson Foodie is Tucson's premier food and dining publication, covering the best restaurants, events, and culinary experiences in Southern Arizona.

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@Sonoranrestaurantweek is almost here! September 4–13!🌵

This year, Flying V at @loewsventana is featuring a special K4 Ranch Prime Beef Tasting for $55.🥩

Dry-Aged Beef Tartare
Koji-Honey Vinaigrette, Fermented Tomato, Shallot, Pistachio, Fry Bread I *+18 add Flying V Special Reserve Caviar I *Casa Madero - Chardonnay — Valle de Parras, Mexico 

Tournedos of Filet Mignon
Desert Pearl Oyster Mushrooms, Del Bac Demi Glace, Our Beef Garum, Chives I Family Style: Hayden Mills Polenta, Farmer’s Market Featured Vegetables I *Merkin — Chupacabra Red - (Grenache, Mourvédre, Syrah, Petite Sirah) - Willcox, Arizona 

Caramel Butter Cake
Exo Coffee-Toffee Sauce, Bread Syrup, Preserved Jujube Chutney, Bone Marrow Ice Cream I *Flying Leap — Sangiovese – Elgin, Arizona 

See menus and build your itinerary on Tucsonfoodie/srw👈
#tucsonfoodie #tucsonevents@Sonoranrestaurantweek is almost here! September 4–13!🌵 This year, Flying V at @loewsventana is featuring a special K4 Ranch Prime Beef Tasting for $55.🥩 Dry-Aged Beef Tartare Koji-Honey Vinaigrette, Fermented Tomato, Shallot, Pistachio, Fry Bread I *+18 add Flying V Special Reserve Caviar I *Casa Madero - Chardonnay — Valle de Parras, Mexico Tournedos of Filet Mignon Desert Pearl Oyster Mushrooms, Del Bac Demi Glace, Our Beef Garum, Chives I Family Style: Hayden Mills Polenta, Farmer’s Market Featured Vegetables I *Merkin — Chupacabra Red - (Grenache, Mourvédre, Syrah, Petite Sirah) - Willcox, Arizona Caramel Butter Cake Exo Coffee-Toffee Sauce, Bread Syrup, Preserved Jujube Chutney, Bone Marrow Ice Cream I *Flying Leap — Sangiovese – Elgin, Arizona See menus and build your itinerary on Tucsonfoodie/srw👈 #tucsonfoodie #tucsonevents
TOMORROW! An evening of food, plants, and connection returns under the desert sky.🌵✨

In partnership with @salus.healers, join us tomorrow, August 29, at @tohonochul for Desert Magic, a one-night celebration of the edible and medicinal beauty of the Sonoran Desert. Stroll the gardens, drink in hand, and discover chef and wellness stations along the way. 

🌿WELLNESS PRACTITIONERS offering sound healing, massage, somatic therapy, readings, reiki, plant walks, workshops & more: @awakenedwombs | @curavidabodywork | @dharmawellness.center | @drkorigiudici | Ease Bodywork | @itsme.emmav | @healingspiritsoaks | @marie.heartnectar | @innerblissenergetics | @jessi.kyte.bodywork | Medicine Within | @monsoonmystics | @morosomedicalcenter | @intuitive_readings_by_zev | @sugarmelovetucson | @tantricheart_coaching | @gathering_point_ | @thehealinghubaz | The Somatic Sound 

🔥FOOD: @el_chef_padilla (@copperashculinary) | @landofmilknhoney (@tohonochulgardenbistro) | @chefdevonsanner (@sandpcreative) | Chef Gracie Soto (@anita_st_market) | @chefjosetucson (@ameliastucson) | @kenneth.foy | Obie Hindman & @tuckerhartford (@tucsoncityofgastronomy & @solpuebloprovisions) | @archimagirus_cultro (@scratchingtheplate)

🥣 SOUNDS @tucsonmodernjazzquartet | DJ Sets by Rosa Dragona & LaDev

Ticket includes wellness stations, herb walks, workshops, sound healing, & botanical drinks.

Tap the link in bio to grab yours! 🎟️✨ 

Video by @dalton.voss 
#tucsonfoodie #tucsoneventTOMORROW! An evening of food, plants, and connection returns under the desert sky.🌵✨ In partnership with @salus.healers, join us tomorrow, August 29, at @tohonochul for Desert Magic, a one-night celebration of the edible and medicinal beauty of the Sonoran Desert. Stroll the gardens, drink in hand, and discover chef and wellness stations along the way. 🌿WELLNESS PRACTITIONERS offering sound healing, massage, somatic therapy, readings, reiki, plant walks, workshops & more: @awakenedwombs | @curavidabodywork | @dharmawellness.center | @drkorigiudici | Ease Bodywork | @itsme.emmav | @healingspiritsoaks | @marie.heartnectar | @innerblissenergetics | @jessi.kyte.bodywork | Medicine Within | @monsoonmystics | @morosomedicalcenter | @intuitive_readings_by_zev | @sugarmelovetucson | @tantricheart_coaching | @gathering_point_ | @thehealinghubaz | The Somatic Sound 🔥FOOD: @el_chef_padilla (@copperashculinary) | @landofmilknhoney (@tohonochulgardenbistro) | @chefdevonsanner (@sandpcreative) | Chef Gracie Soto (@anita_st_market) | @chefjosetucson (@ameliastucson) | @kenneth.foy | Obie Hindman & @tuckerhartford (@tucsoncityofgastronomy & @solpuebloprovisions) | @archimagirus_cultro (@scratchingtheplate) 🥣 SOUNDS @tucsonmodernjazzquartet | DJ Sets by Rosa Dragona & LaDev Ticket includes wellness stations, herb walks, workshops, sound healing, & botanical drinks. Tap the link in bio to grab yours! 🎟️✨ Video by @dalton.voss #tucsonfoodie #tucsonevent
SPECIAL DINNERS DURING SONORAN RESTAURANT WEEK🌵

@Sonoranrestaurantweek is ONE WEEK AWAY! In addition to prix-fixe menus around Tucson, @sonoranrestaurantweek features a lineup of special dinners and one very special brunch. Here’s the schedule:

FRIDAY, SEPTEMBER 4 • 6 PM
Inca’s Peruvian Cuisine Special Dinner
📍 @incasperuviancuisine 
 
SATURDAY, SEPTEMBER 5 • 6 PM
Penca Special Dinner
📍 @pencarestaurante 

SUNDAY, SEPTEMBER 6 • 11 AM–2 PM
Sonoran Restaurant Week Brunch Takeover
📍 Flying V @loewsventana 

SUNDAY, SEPTEMBER 6 • 6:30 PM
Whole Hog BBQ Dinner
📍 @bashfulbanditbbq 

TUESDAY, SEPTEMBER 8 • 6 PM
Sunshine Wine Special Dinner
📍 @sunshine_wine_tucson with @queenofcupswines 

WEDNESDAY, SEPTEMBER 9 • 6 PM
BOCA by Chef Maria Mazon Special Dinner
📍 @bocatucson 

THURSDAY, SEPTEMBER 10 • 6 PM
Bacio Italiano Special Dinner with @vertigo.wines 
📍 @bacio.italianoaz 

FRIDAY, SEPTEMBER 11 • 6 PM
Cielos Special Dinner
📍 @cielostucson 

SATURDAY, SEPTEMBER 12 • 6 PM 
Nana’s Kitchen Special Dinner with @rombauervineyards 
📍 @nanas_kitchen_2008 

SUNDAY, SEPTEMBER 13 • 6 PM
Wild Garlic Grill Special Dinner
📍 @wildgarlicgrillofficial 

Several events have limited seating and require tickets or reservations, so plan ahead!

Sonoran Restaurant Week runs September 4–13. Tap the link in our bio for menus, tickets, reservations, and more.❤️

#SRW2026 #sonoranrestaurantweek
#tucsonfoodie #tucsonfoodieeventsSPECIAL DINNERS DURING SONORAN RESTAURANT WEEK🌵 @Sonoranrestaurantweek is ONE WEEK AWAY! In addition to prix-fixe menus around Tucson, @sonoranrestaurantweek features a lineup of special dinners and one very special brunch. Here’s the schedule: FRIDAY, SEPTEMBER 4 • 6 PM Inca’s Peruvian Cuisine Special Dinner 📍 @incasperuviancuisine SATURDAY, SEPTEMBER 5 • 6 PM Penca Special Dinner 📍 @pencarestaurante SUNDAY, SEPTEMBER 6 • 11 AM–2 PM Sonoran Restaurant Week Brunch Takeover 📍 Flying V @loewsventana SUNDAY, SEPTEMBER 6 • 6:30 PM Whole Hog BBQ Dinner 📍 @bashfulbanditbbq TUESDAY, SEPTEMBER 8 • 6 PM Sunshine Wine Special Dinner 📍 @sunshine_wine_tucson with @queenofcupswines WEDNESDAY, SEPTEMBER 9 • 6 PM BOCA by Chef Maria Mazon Special Dinner 📍 @bocatucson THURSDAY, SEPTEMBER 10 • 6 PM Bacio Italiano Special Dinner with @vertigo.wines 📍 @bacio.italianoaz FRIDAY, SEPTEMBER 11 • 6 PM Cielos Special Dinner 📍 @cielostucson SATURDAY, SEPTEMBER 12 • 6 PM Nana’s Kitchen Special Dinner with @rombauervineyards 📍 @nanas_kitchen_2008 SUNDAY, SEPTEMBER 13 • 6 PM Wild Garlic Grill Special Dinner 📍 @wildgarlicgrillofficial Several events have limited seating and require tickets or reservations, so plan ahead! Sonoran Restaurant Week runs September 4–13. Tap the link in our bio for menus, tickets, reservations, and more.❤️ #SRW2026 #sonoranrestaurantweek #tucsonfoodie #tucsonfoodieevents
Win 2 tickets to Oktober Foodie Fest! 🍺🥨🌭

Oktober Foodie Fest returns to @corbettstucson on Saturday, September 26th. It’s Oktoberfest, but with a Tucson Foodie flavor all its own!

🎶 Live Music 🍺 Craft Beer Garden 🏋️ Classic Contests 🥨 Authentic German Eats ✚ MORE! 

Here’s how to enter:
1️⃣ Follow @tucsonfoodie & @corbettstucson
2️⃣ Tag 1 friend (Your best brat-buddy🌭) and comment “Let’s go to OktoberFoodieFest!”
3️⃣ We’ll draw our winner for the two passes Friday 8/28 at 9:45AM, just before tickets go on sale at 10:00 AM!

Tickets on sale Friday 8/28 @ 10AM PT
Tickets & more info ➡️ oktoberfoodiefest.eventbrite.com

⚠️ Note for Foodie Insider Members: Check your email for your 50% event discount code!Win 2 tickets to Oktober Foodie Fest! 🍺🥨🌭 Oktober Foodie Fest returns to @corbettstucson on Saturday, September 26th. It’s Oktoberfest, but with a Tucson Foodie flavor all its own! 🎶 Live Music 🍺 Craft Beer Garden 🏋️ Classic Contests 🥨 Authentic German Eats ✚ MORE! Here’s how to enter: 1️⃣ Follow @tucsonfoodie & @corbettstucson 2️⃣ Tag 1 friend (Your best brat-buddy🌭) and comment “Let’s go to OktoberFoodieFest!” 3️⃣ We’ll draw our winner for the two passes Friday 8/28 at 9:45AM, just before tickets go on sale at 10:00 AM! Tickets on sale Friday 8/28 @ 10AM PT Tickets & more info ➡️ oktoberfoodiefest.eventbrite.com ⚠️ Note for Foodie Insider Members: Check your email for your 50% event discount code!